Conference Presentations

Conferences 2024

Singapore Health and Biomedical Congress 2024

Location: Singapore
Date: October 2024

Oral Presentation

Yi Jin Leow – Silver Award Winner, Singapore Young Investigator Award (Clinical Research)
Title: Mild Behavioral Impairment as a Clinical Correlate of Early Neurodegeneration

Poster Presentations

Qiu Bocheng – Retinal Biomarkers for Early Detection of Cognitive Impairment

Pricilia Tanoto – The Free and Cued Selective Reminding Test (FCSRT) as a Screening Tool for Mild Cognitive Impairment (MCI) in a Multiethnic Population

Gursimar Bhalla – Cognitive Reserve in Southeast Asian Working Adults: Influence of Behavioural and Lifestyle Factors

Ashwati Vipin – Automatic Brain Segmentation with AQUA: A Comparative Validation Study in the Southeast Asian BIOCIS Cohort

Alzheimer’s Association International Conference® (AAIC®) 2024

Location: Philadelphia, USA
Date: July 2024

Oral Presentation

Yi Jin Leow – Association between Cortical Thickness and Mild Behavioral Impairment in a Southeast Asian Population – Biomarkers and Cognition Study, Singapore (BIOCIS)

Poster Presentations

Yi Jin Leow – Association between Blood-based Biomarkers of Alzheimer’s Disease and Endothelial Function with Mild Behavioral Impairment in a Southeast Asian Population – Biomarkers and Cognition Study, Singapore (BIOCIS)

Yi Jin Leow – Mild Behavioral Impairment Association with the Visual Cognitive Assessment Test (VCAT) in a Southeast Asian Population with Vascular Mild Cognitive Impairment – Biomarkers and Cognition Study, Singapore (BIOCIS)

Pricilia Tanoto – Usefulness of Visual Cognitive Assessment Test in Detecting Vascular MCI in a Southeast Asian Cohort

Pricilia Tanoto – Usefulness of Test of Practical Judgement (TOP-J) for Detecting Mild Cognitive Impairment (MCI) in Southeast Asian Population

Adnan Azam Mohammed – A Personalised Digital Multidomain Lifestyle Intervention to Slow Cognitive Decline: Study Design and Protocol

Gurveen Kaur Sandhu – Plasma Biomarkers Independently Moderate the Relationship Between Cognition and Volumetric White Matter Hyperintensities in a Southeast Asian Non-Demented but At-Risk Community Population

Smriti Ghildiyal – ApoE4 Moderates the Association Between Vascular Risk, Cerebral Perfusion, and Cognitive Performance in a Southeast Asian Population

18th International Congress of the Asian Society Against Dementia (ASAD 2024)

Location: Penang, Malaysia
Date: August 2024

Award Winners

Ashwati Vipin – Young Investigator Award 1st Prize

Mohammed Adnan Azam. Young Research Award 1st Prize

Timothy Bang Hao Aw. Young Research Award 2nd Prize

Faith Phemie Lee Hui En. Young Research Award 5th Prize

Oral Presentations

Ashwati Vipin – Automatic Brain Segmentation with AI-Based AQUA Software: A Comparative Validation Study in the Southeast Asian BIOCIS Cohort

Pricilia Tanoto – The Free and Cued Selective Reminding Test (FCSRT) as a Screening Tool for Mild Cognitive Impairment (MCI) in a Multiethnic Population

Poster Presentations

Adnan Azam Mohammed – Development and Validation of the ReCOGnAIze App for Detection of Mild Cognitive Impairment (MCI) and Vascular MCI Using Digital Gamified Assessments

Yi Jin Leow – Blood Biomarkers and Neuropsychiatric Symptoms, Pathways to Early Detection of Cognitive Impairment in a Southeast Asian Population – Biomarkers and Cognition Study, Singapore (BIOCIS)

Timothy Bang Hao Aw – Plasma P-Tau181 is Associated with Executive Dysfunction in an Aβ-Negative Southeast Asian Population – Biomarkers and Cognition Study, Singapore (BIOCIS)

Shan Yao Liew – Demographic, Clinical, and Neuropsychological Profiles of Urine Amyloid Test Kit Positivity

Bocheng Qiu – Retinal Biomarkers for Early Detection of Cognitive Impairment

Faith Phemie Lee Hui En – Neuropsychiatric and Neurobehavioural Profile of Frail Southeast Asians with and Without Cerebrovascular Disease

Rasyiqah bte Shaik Mohamed Salim – Investigating Structural Neuroimaging Variances Using Voxel-Based Morphometry (VBM) Between Behaviourally Impaired and Non-Impaired Individuals – Biomarkers and Cognition Study, Singapore (BIOCIS)

2022

Nagaendran Kandiah, See Ann Soo, Levinia Lim, Yi Jin Leow, Ashwati Vipin, Kok Pin Ng. Development and Validation of a Cognitive Evaluation tool for Multilingual Populations: The Visual Cognitive Assessment Test (VCAT). Alzheimer’s Association International Conference. San Diego, USA, July 31-Aug 4 2022.

Ashwati Vipin, Dilip Kumar, See Ann Soo, Fatin Zahra Zailan, Yi Jin Leow, Chen Ling Koh, Adeline Su Lyn Ng, Kok Pin Ng and Nagaendran Kandiah. APOE4 Carrier Status Determines Association Between White Matter Disease and Grey Matter Atrophy in Early-Stage Dementia. Alzheimer’s Association International Conference. San Diego, USA, July 31-Aug 4 2022.

Yi Jin Leow, Seyed Ehsan Saffari, Esther Vanessa Chua, Mei Mei Nyu, Nur Nazaria Baharudin, Fennie Choy Chin Wong, Sheng Chun Ng, Kok Pin Ng, Nagaendran Kandiah.Pre-stroke Chronic Cerebrovascular Disease is a Major Determinant for Response to Structured Cognitive Rehabilitation following Acute Ischemic Strokes. Alzheimer’s Association International Conference. San Diego, USA, July 31-Aug 4 2022.

Gurveen Kaur Sandhu, Fatin Zahra Zailan , Ashwati Vipin, Soo See Ann, Dilip Kumar, Kok Pin Ng, Nagaendran Kandiah. Correlation between plasma Oligomeric Amyloid Beta and performance on the language neutral Visual Cognitive Assessment Test in a Southeast Asian population. Alzheimer’s Association International Conference. San Diego, USA, July 31-Aug 4 2022.

Dilip Kumar, Chathuri Yatawara, Brian Wang, Benjamin Wong, Jayne Yi Tan, Fatin Zahra Zailan, Kok Pin Ng, Nagaendran Kandiah. APOE4 and Confluent White Matter Hyperintensities Have a Synergistic Effect on Episodic Memory Impairment in Prodromal Dementia. Alzheimer’s Association International Conference. San Diego, USA, July 31-Aug 4 2022.

See Ann Soo, Kok Pin Ng, Dilip Kumar, Seyed Ehsan Saffari, Nagaendran Kandiah. The moderating effects of education and white matter hyperintensity on mild behavioural impairment. Alzheimer’s Association International Conference. San Diego, USA, July 31-Aug 4 2022.

Kok Pin Ng, See Ann Soo, Gurveen Kaur Sandhu, Fatin Zahra Zailan, Seyed Ehsan Saffari, Nagaendran Kandiah. Plasma Oligomeric Amyloid-β partially mediates the effects of Diabetes Mellitus on Cognition in Mild Cognitive Impairment. Alzheimer’s Association International Conference. San Diego, USA, July 31-Aug 4 2022.

2021

Vipin, A… Kandiah,N. Amyloid-Tau-Neurodegeneration (ATN) Profiles and Influence of Age-of-onset on Cognitive Trajectories in a Southeast Asian Cohort: SYNC Project. SingHealth Duke-NUS Scientific Congress. Virtual Conference. September 17-18 2021.

Soo, SA… Kandiah,N.. The Association of APOE4 with Mild Behavioral Impairment SingHealth Duke-NUS Scientific Congress. Virtual Conference. September 17-18 2021.

Kumar, D… Kandiah, N. The neurobehavioural syndrome of mild behavioural impairment is associated with reduced functional connectivity in major cerebral functional networks. SingHealth Duke-NUS Scientific Congress. Virtual Conference. September 17-18 2021.

Kumar, D… Kandiah ,N. The relationship between APOE E4, white matter hyperintensities and episodic memory at prodromall dementia stage.. SingHealth Duke-NUS Scientific Congress. Virtual Conference. September 17-18 2021.

Vipin, A… Kandiah, N. Amyloid-Tau-Neurodegeneration (ATN) Profiles and Influence of Age-of-onset on Cognitive Trajectories in a Southeast Asian Cohort: SYNC Project. Alzheimer’s Association International Conference. Virtual Conference, July 26-30 2021.

Wong, F.C.C… Kandiah, N. Findings from an Asian post‐stroke cognitive impairment intervention programme. Alzheimer’s Association International Conference. Virtual Conference, July 26-30 2021.

Vipin, A… Kandiah, N. Amyloid-Tau-Neurodegeneration profiles and effect of age on the association between amyloid burden and longitudinal cognition. NNI Neuroscience Research Day, 30th April 2021.

2021

Soo SA, Zailan FZ, Tan JY, Sandhu GK, Wong BYX, Wang BZ, Ng ASL, Chiew HJ, Ng KP, Kandiah N. Safety and Usefulness of Lumbar Puncture for the Diagnosis and Management of Young-Onset Cognitive Disorders. 2022. Accepted In Journal of Alzheimer’s Disease.

Vipin A, Satish V, Saffari SE, Koh W, Lim L, Silva E, Nyu MM, Choong TM, Chua E, Lim L, Ng ASL, Chiew HJ, Ng KP, Kandiah N. Dementia in Southeast Asia: influence of onset-type, education, and cerebrovascular disease. Alzheimers Res Ther. 2021 Nov 30;13(1):195. doi: 10.1186/s13195-021-00936-y. PMID: 34847922; PMCID: PMC8630908.

Wong FCC, Saffari SE, Yatawara C, Ng KP, Kandiah N; Alzheimer’s Disease Neuroimaging Initiative. Influence of White Matter Hyperintensities on Baseline and Longitudinal Amyloid-β in Cognitively Normal Individuals. J Alzheimers Dis. 2021;84(1):91-101. doi: 10.3233/JAD-210333. PMID: 34511497.

Ng KP, Cheng GH, Yatawara C, Rosa-Neto P, Gauthier S, Kandiah N; Alzheimer’s Disease Neuroimaging Initiative. Baseline Neurodegeneration Influences the Longitudinal Effects of Tau on Cognition. J Alzheimers Dis. 2021;82(1):159-167. doi: 10.3233/JAD-201425. PMID: 33998536.

Soo SA, Ng KP, Wong F, Saffari SE, Yatawara C, Ismail Z, Kandiah N. The Association Between Diabetes Mellitus and Mild Behavioral Impairment Among Mild Cognitive Impairment: Findings from Singapore. J Alzheimers Dis. 2021;82(1):411-420. doi: 10.3233/JAD-210037. PMID: 34024829.

Vipin A, Wong BYX, Kumar D, Low A, Ng KP, Kandiah N. Association between white matter hyperintensity load and grey matter atrophy in mild cognitive impairment is not unidirectional. Aging (Albany NY). 2021 Apr 16;13(8):10973-10988. doi: 10.18632/aging.202977. Epub 2021 Apr 16. PMID: 33861727; PMCID: PMC8109133.

Ng KP, Chiew HJ, Hameed S, Ting SKS, Ng A, Soo SA, Wong BYX, Lim L, Yong ACW, Mok VCT, Rosa-Neto P, Dominguez J, Kim S, Hsiung GYR, Ikeda M, Miller BL, Gauthier S, Kandiah N. Frontotemporal dementia and COVID-19: Hypothesis generation and roadmap for future research. Alzheimers Dement (N Y). 2021 Jan 15;6(1):e12085. doi: 10.1002/trc2.12085. PMID: 33490361; PMCID: PMC7810128.

Kandiah N, Chan YF, Chen C, Dasig D, Dominguez J, Han SH, Jia J, Kim S, Limpawattana P, Ng LL, Nguyen DT, Ong PA, Raya-Ampil E, Saedon N, Senanarong V, Setiati S, Singh H, Suthisisang C, Trang TM, Turana Y, Venketasubramanian N, Yong FM, Youn YC, Ihl R. Strategies for the use of Ginkgo biloba extract, EGb 761® , in the treatment and management of mild cognitive impairment in Asia: Expert consensus. CNS Neurosci Ther. 2021 Feb;27(2):149-162. doi: 10.1111/cns.13536. Epub 2020 Dec 22. PMID: 33352000; PMCID: PMC7816207.

2020

Vipin A… Kandiah, N. Threshold of white matter hyperintensity volume determines negative and positive associations between grey matter volume and hypertension. Alzheimer’s Association International Conference. Virtual Conference, July 27-31 2020

Soo, SA… Kandiah, N. Mild Behaviour Impairment Checklist (MBI‐C): Is there a difference in ratings between patient and close informant? Alzheimer’s Association International Conference. Virtual Conference, July 27-31 2020

Kumar, D… Kandiah, N. Differential effects of confluent and non-confluent white matter hyperintensities on functional connectivity in mild cognitive impairment. Alzheimer’s Association International Conference. Virtual Conference, July 27-31 2020.

Ong, A.P.X… Kandiah, N. Stroke Memory Rehabilitation (SMaRT) programme for mild ischemic stroke: preliminary findings. Alzheimer’s Association International Conference. Virtual Conference, July 27-31 2020

Choong, T.Y.,… Kandiah, N. OWOW! Six years on, what have we learned? Experience and perspectives on a cognitive interventional programme for persons with dementia. Alzheimer’s Association International Conference. Virtual Conference, July 27-31 2020

Chiew, H.J., … Kandiah, N. Assessing and improving primary care physician confidence in the recognition of young-onset and atypical dementia: A pilot intervention. Alzheimer’s Association International Conference. Virtual Conference, July 27-31 2020

Lim, L., … Kandiah, N. Posterior cortical atrophy in Southeast Asia. Alzheimer’s Association International Conference. Virtual Conference, July 27-31 2020

Wong, F.C.C…. Kandiah, N. Cerebrovascular disease influences hippocampal subfield atrophy in mild cognitive impairment: Neuroimaging / New imaging methods. Alzheimer’s Association International Conference. Virtual Conference, July 27-31 2020

Wong, F.C.C… Kandiah, N. Characterising mild behavioural impairment in Asian mild cognitive impairment and cognitively normal individuals. Alzheimer’s Association International Conference. Virtual Conference, July 27-31 2020

2019

Wang, B… Kandiah, N. Identification of novel candidate autoantibody biomarkers for the early diagnosis of Alzheimer’s Disease. 13th International Congress of the Asian Society Against Dementia and 6th International Neurocognitive symposium.

Wong, B.Y.X.,… Kandiah, N. Association of CSF biomarkers and Medial Temporal Lobe Atrophy on Amnestic and Non Amnestic Phenotypes of Alzheimer’s Disease. 13th International Congress of the Asian Society Against Dementia and 6th International Neurocognitive symposium.

Zailan, F.Z…. Kandiah, N. Correlation between plasma and CSF Ab in patients with MCI and Alzheimer’s Disease. NNI Neuroscience Research Day.